3,4,5-Tricaffeoylquinic acid
This research compound, 3,4,5-Tricaffeoylquinic acid, suppresses TLR4 expression to inhibit Akt, ERK, and NF-κB pathway activation, thereby reducing TNF-α and LPS-induced inflammatory mediator production in keratinocytes. It is a useful tool for studying inflammatory skin disease mechanisms in both cellular and animal models.
Product Specifications
CAS Number
86632-03-3
Field of Research
Cell Biology, Infectious Disease & Virology, Protein Biochemistry, Signal Transduction
Smiles
OC (=O) [C@@]1 (O) C[C@@H] (OC (=O) \C=C\c2ccc (O) c (O) c2) [C@H] (OC (=O) \C=C\c2ccc (O) c (O) c2) [C@@H] (C1) OC (=O) \C=C\c1ccc (O) c (O) c1
Molecular Formula
C34H30O15
Molecular Weight
678.59
Storage Conditions
-20°C
Notes
For research use only.
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