3',4',7-Trihydroxyisoflavone
3',4',7-Trihydroxyisoflavone is a soy-derived isoflavone that acts as an inhibitor of Cot (MAP3K8) and MKK4. It exhibits anticancer and antiangiogenic properties in vitro and has been shown in murine studies to enhance memory via cholinergic and BDNF pathways, as well as improve glucocorticoid-impaired skin barrier function relevant to atopic dermatitis research.
Product Specifications
CAS Number
485-63-2
Product Name Alternative
MKK4, MAP3K8, 3',4',7-Trihydroxyisoflavone, 3',4',7Trihydroxyisoflavone, 3',4',7 Trihydroxyisoflavone
Field of Research
Cell Biology, Signal Transduction
Purity
98.95% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (12.21 mM) ; DMSO:80 mg/mL (296.03 mM)
Smiles
Oc1ccc2c (c1) occ (-c1ccc (O) c (O) c1) c2=O
Molecular Formula
C15H10O5
Molecular Weight
270.24
Storage Conditions
Store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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