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APC Conjugated Human CD8 alpha Recombinant Mouse Monoclonal Antibody [PSH04-94]

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen-presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Two alternative transcripts encoding distinct isoforms, one membrane associated and one secreted, have been identified.

Product Specifications

Product Name Alternative

alpha polypeptide (p32) antibody CD_antigen=CD8a antibody CD8 antibody CD8 antigen alpha polypeptide antibody CD8 antigen alpha polypeptide (p32) antibody CD8 antigen, alpha polypeptide (p32) antibody CD8a antibody CD8A antigen antibody CD8A molecule antibody CD8A_HUMAN antibody Leu2 antibody Leu2 T lymphocyte antigen antibody Ly 2 antibody Ly 35 antibody Ly B antibody Ly2 antibody Ly3 antibody Ly35 antibody LyB antibody Lyt 2.1 lymphocyte differentiation antigen (AA at 100) antibody LYT3 antibody MAL antibody OKT8 T cell antigen antibody OTTHUMP00000160760 antibody OTTHUMP00000160764 antibody OTTHUMP00000203528 antibody OTTHUMP00000203721 antibody p32 antibody T cell antigen Leu2 antibody T cell co receptor antibody T lymphocyte differentiation antigen T8/Leu 2 antibody T-cell surface glycoprotein CD8 alpha chain antibody T-cell surface glycoprotein Lyt 2 antibody T-lymphocyte differentiation antigen T8/Leu-2 antibody T8 T cell antigen antibody T8/Leu-2 T-lymphocyte differentiation antigen antibody

Abbreviation

CD8A

Swiss Prot

P01732 Human

Cellular Locus

Cell membrane; Secreted.

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant protein within

Isotype

IgG1

Clone

PSH04-94

Conjugation

APC

Type

Recombinant Mouse monoclonal Antibody

Applications

FC

Positive Control

Human peripheral blood lymphocytes.

Dilution

FC: 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

Supplied in phosphate-buffered solution, pH 7.2, containing 0.2% ProClean 950 and BSA.

Molecular Weight

Predicted band size: 26 kDa

Storage Conditions

Store at 2°C to 8°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes

CAS Number

9000-83-3

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