7-Hydroxyaristolochic acid A
7-Hydroxyaristolochic acid A is a nephrotoxic and carcinogenic derivative of aristolochic acid. It induces apoptosis in renal NRK-52E cells via COX-2/PGE2 and inhibits the APE1/Nrf2/HO-1 antioxidant pathway, making it a tool for studying nephrotoxicity mechanisms in vitro.
Product Specifications
CAS Number
79185-75-4
Product Name Alternative
7 Hydroxyaristolochic acid A, 7Hydroxyaristolochic acid A, 7-Hydroxyaristolochic acid A
Field of Research
Cell Biology, Molecular Biology
Purity
99.47% (May vary between batches)
Solubility
DMSO:80 mg/mL (223.92 mM)
Smiles
O=C (C1=CC2=C (C3=C4C=CC (O) =C (C4=CC ([N+] ([O-]) =O) =C13) OC) OCO2) O
Molecular Formula
C17H11NO8
Molecular Weight
357.27
Storage Conditions
Keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
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