Cucurbitacin D
Cucurbitacin D is a bioactive triterpenoid from Ecballium elaterium with demonstrated anticancer properties. It inhibits proliferation and metabolic pathways in various cancer cell lines, including prostate, liver, and leukemia models, by targeting key signaling cascades such as JAK/STAT3 and PI3K/Akt. This compound also acts as a novel inflammasome activator in macrophages, making it a valuable tool for oncology and immunology research.
Product Specifications
CAS Number
3877-86-9
Product Name Alternative
Apoptosis, Cucurbitacin D, IL Receptor, JNK, STAT
Field of Research
Cell Biology, Metabolism Research, Signal Transduction
Purity
97.69% (May vary between batches)
Solubility
DMSO:80 mg/mL (154.84 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (6.39 mM)
Smiles
CC (C) (O) \C=C\C (=O) [C@] (C) (O) [C@H]1[C@H] (O) C[C@@]2 (C) [C@@H]3CC=C4[C@@H] (C[C@H] (O) C (=O) C4 (C) C) [C@]3 (C) C (=O) C[C@]12C
Molecular Formula
C30H44O7
Molecular Weight
516.67
Storage Conditions
Keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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