2'-Hydroxychalcone
2'-Hydroxychalcone is a synthetic flavonoid intermediate with demonstrated bioactivity in research models. In vitro, it induces cytotoxicity via oxidative stress in HepG2 cells and inhibits pro-inflammatory adhesion molecule expression. In vivo, a nanoemulsion formulation has shown antifungal efficacy against Candida parapsilosis in a zebrafish (Danio rerio) model.
Product Specifications
CAS Number
1214-47-7
Product Name Alternative
E-selectin, Fungal, ICAM-1, 1 (2 Hydroxyphenyl) 3 phenyl 2 propenone, 1 (2Hydroxyphenyl) 3phenyl2propenone, 2'-Hydroxychalcone, TNF-α, VCAM1
Field of Research
Cell Biology, Infectious Disease & Virology, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (122.63 mM)
Smiles
Oc1ccccc1C (=O) \C=C\c1ccccc1
Molecular Formula
C15H12O2
Molecular Weight
224.25
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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