6-Dehydrogingerdione
6-Dehydrogingerdione enhances TRAIL-induced apoptosis in Hep G2 cells via ROS-mediated DR5 upregulation and p53 activation. This compound is a useful research tool for studying p53-dependent apoptotic pathways and TRAIL sensitization mechanisms in cancer cell models, including hepatoblastoma, in vitro.
Product Specifications
CAS Number
76060-35-0
Product Name Alternative
6Dehydrogingerdione, 6-Dehydrogingerdione, 6 Dehydrogingerdione, 1-Dehydro-6-gingerdione, COX, NOS, PGE, Prostaglandin Receptor
Field of Research
Cell Biology
Purity
96.98% (May vary between batches)
Solubility
DMSO:80 mg/mL (275.53 mM)
Smiles
C (=C/C (CC (CCCCC) =O) =O) \C1=CC (OC) =C (O) C=C1
Molecular Formula
C17H22O4
Molecular Weight
290.35
Storage Conditions
Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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