Apostatin-1
Apostatin-1 (Apt-1) is a novel small molecule inhibitor that selectively targets the TRAF2-binding domain of TRADD. This mechanism enables its use in vitro and in vivo to investigate TNF signaling pathways, apoptosis, and necroptosis in relevant disease models.
Product Specifications
CAS Number
2559703-06-7
Product Name Alternative
Necroptosis, inflammatory responses, inhibit, Jurkat cells, Inhibitor, HeLa, HT-29, beclin 1, Beclin1, Apoptosis, Apostatin 1, Apostatin1, Apostatin-1, Apt-1, Apt1, Apt 1, Autophagy, Atg6, TRADD, RIP kinase, RIPK1, RIPK, SH-SY5Y, Receptor-interacting protein kinases
Field of Research
Cell Biology, Signal Transduction
Purity
99.08% (May vary between batches)
Solubility
Ethanol:9 mg/mL (26.05 mM) ; DMSO:50 mg/mL (144.72 mM)
Smiles
CN1CCN=C1SC (C (=O) NC1CCCCCC1) c1ccccc1
Molecular Formula
C19H27N3OS
Molecular Weight
345.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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