UNC5293
UNC5293 is a highly potent and selective MERTK inhibitor (Ki = 190 pM) with excellent oral bioavailability. It demonstrates significant selectivity over Axl, Tyro3, and Flt3 and is utilized in leukemia research, particularly for in vivo studies involving bone marrow malignancies.
Product Specifications
CAS Number
2226789-82-6
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
CCC[C@H] (C) Nc1ncc2c (cn ([C@H]3CC[C@H] (O) CC3) c2n1) C1CCN (CC1) C (=O) c1cc (C) nc (C) c1
Molecular Formula
C30H42N6O2
Molecular Weight
518.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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