ALE-0540
ALE-0540 is a small molecule inhibitor that selectively blocks NGF binding to both its p75 and TrkA receptors, thereby disrupting downstream TrkA-mediated signaling and biological activity. This tool compound is used in vitro and in vivo to investigate neurotrophin pathways in pain, neurodegeneration, and cancer research.
Product Specifications
CAS Number
234779-34-1
Product Name Alternative
Trk receptor, TrkA, Trkreceptor, ALE 0540, ALE0540, ALE-0540
Field of Research
Signal Transduction
Purity
97.25% (May vary between batches)
Solubility
DMSO:50 mg/mL (165.98 mM)
Smiles
O=C1C=2C=3C (C (=O) N1NCCO) =CC=CC3C=C (N (=O) =O) C2
Molecular Formula
C14H11N3O5
Molecular Weight
301.25
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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