Integrin alpha V beta 3, Mouse (HEK293, hFc)

Integrin alpha V beta 3 (ITGAV:ITGB3) functions as a receptor for CD40LG, enhancing Lilrb4a inhibitory effects on mast cell activation. It suppresses marginal zone B cell antibody production through Lilrb4a interaction. ITGAV:ITGB3, forming a heterodimer with ITGAV, interacts with ligands such as RAB25, CIB1, FBLN5, and more. It also forms a complex with PTPRZ1 and PTN, stimulating endothelial cell migration. Integrin alpha V beta 3 Protein, Mouse (HEK293, hFc) is a recombinant protein dimer complex containing mouse-derived Integrin alpha V beta 3 protein, expressed by HEK293 , with C-hFc labeled tag. Integrin alpha V beta 3 Protein, Mouse (HEK293, hFc), has molecular weight of 110-135 kDa & 50-60 kDa, respectively.