BCR-ABL-IN-8
BCR-ABL-IN-8 (compound 26f) is a BCR-ABL inhibitor containing trimethoxy group[1].
Product Specifications
CAS Number
1808288-49-4
UNSPSC
12352005
Target
Bcr-Abl
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcr-abl-in-8.html
Purity
99.26
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(OC)=C(C(OC)=C1)OC)NC2=CC=C(C)C(NC(C3=CN=C(NC4=CC=C(C)C(N)=C4)N=C3NC)=O)=C2
Molecular Formula
C30H33N7O5
Molecular Weight
571.63
References & Citations
[1]Liang X, et al. Discovery of 2- ((3-Amino-4-methylphenyl) amino) -N- (2-methyl-5- (3- (trifluoromethyl) benzamido) phenyl) -4- (methylamino) pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Leukemia. J Med Chem. 2016 Mar 10;59 (5) :1984-2004.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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