ETRB Antagonist 1
This small molecule is a dual endothelin receptor antagonist, inhibiting binding to human ETA and ETB receptors with IC50 values of 268 nM and 1810 nM, respectively. It serves as a valuable research tool for investigating the endothelin system in cardiovascular and renal disease models, both in vitro and in vivo.
Product Specifications
CAS Number
290815-30-4
Product Name Alternative
N (6 chloro 5 (2 Methoxyphenoxy) 2 (pyridin 4 yl) pyriMidin 4 yl) 5 Methylpyridine 2 sulfonamide, N (6chloro5 (2Methoxyphenoxy) 2 (pyridin4yl) pyriMidin4yl) 5Methylpyridine2sulfonamide
Field of Research
Pharmacology & Drug Discovery
Purity
98.48% (May vary between batches)
Smiles
COc1ccccc1Oc1c (Cl) nc (nc1NS (=O) (=O) c1ccc (C) cn1) -c1ccncc1
Molecular Formula
C22H18ClN5O4S
Molecular Weight
483.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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