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Aβ42-IN-2

Aβ42-IN-2 is a potent γ-secretase modulator with an IC50 of 6.5 nM against Aβ42. This small molecule is a valuable research tool for investigating Alzheimer's disease pathogenesis and potential therapeutic strategies in both cellular and animal models.

Product Specifications

CAS Number

1914989-80-2

Product Name Alternative

Aβ42IN2, Aβ42-IN-2, Aβ42 IN 2, Abeta42-IN-2, Ab42-IN-2, Gammasecretase, γ-secretase

Field of Research

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Purity

98.09% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.65 mM) ; DMSO:50 mg/mL (116.14 mM)

Smiles

COc1ccc (cc1) [C@H] (C) Nc1nnc (cc1C) -c1ccc (c (OC) n1) -n1cnc (C) c1

Molecular Formula

C24H26N6O2

Molecular Weight

430.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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