ZW4864 free base
ZW4864 (free base) is an orally bioavailable small molecule that selectively inhibits the β-catenin/BCL9 protein-protein interaction with a Ki of 0.76 μM. This inhibitor is a valuable research tool for studying Wnt/β-catenin signaling in oncology, suitable for both in vitro biochemical assays and in vivo pharmacokinetic studies.
Product Specifications
CAS Number
2632259-92-6
Product Name Alternative
Betacatenin, beta-catenin, bcatenin, Wnt/betacatenin, Wnt/b-catenin, Wnt, Wnt/β-catenin, βcatenin, β-catenin, ZW4864 free base, ZW4864, ZW-4864, ZW 4864
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
99.54% (May vary between batches)
Solubility
DMSO:90 mg/mL (157.7 mM)
Smiles
CC (C) (Oc1cccc (c1) N1CCC[C@H] (C1) C (=O) N (Cc1ccc (cc1) -c1cn[nH]c1) C1CC1) C (=O) N1CCNCC1
Molecular Formula
C33H42N6O3
Molecular Weight
570.72
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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