AP-1/NF-κB activation inhibitor 1
This small molecule inhibitor potently suppresses AP-1 and NF-κB-driven transcriptional activation (IC50 ~1 μM) without affecting basal β-actin promoter activity. It effectively reduces pro-inflammatory cytokine production, such as IL-2 and IL-8, making it a valuable tool for studying inflammation and immune signaling pathways in cellular models.
Product Specifications
CAS Number
188936-12-1
Product Name Alternative
AP 1/NF κB activation inhibitor 1, AP-1/NF-kappaB activation inhibitor 1, AP-1/NF-kB activation inhibitor 1, AP1/NFκB activation inhibitor 1, AP-1/NF-κB activation inhibitor 1, AP-1, DNA Synthesis, DNASynthesis, NFkB, NFκB, NF-kB, NF-κB, RNASynthesis, RNA Synthesis
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.52% (May vary between batches)
Solubility
DMSO:225 mg/mL (653.59 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (14.52 mM)
Smiles
CCOC (=O) c1cnc (nc1NN1C (=O) C=C (C) C1=O) C (F) (F) F
Molecular Formula
C13H11F3N4O4
Molecular Weight
344.25
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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