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SRI 37892

SRI 37892 is a potent small-molecule inhibitor targeting Frizzled-7 (Fzd7), effectively suppressing canonical Wnt/β-catenin signaling. This activity reduces cancer cell viability, making it a valuable tool for in vitro and in vivo research in oncology, particularly for studying Wnt-driven cancers.

Product Specifications

CAS Number

1030769-75-5

Product Name Alternative

FZD7, bcatenin, betacatenin, beta-catenin, Wnt, Wnt/betacatenin, Wnt/b-catenin, Wnt/β-catenin, βcatenin, SRI37892, SRI-37892, SRI 37892

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Purity

98.92% (May vary between batches)

Solubility

DMSO:50 mg/mL (107.4 mM)

Smiles

C (NC1=NC (=CS1) C=2C=C3C (=CC2) NC (=O) CC3) (=O) C4=CC=C (N5C=6C (N=C5) =CC=CC6) C=C4

Molecular Formula

C26H19N5O2S

Molecular Weight

465.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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