SRI 37892
SRI 37892 is a potent small-molecule inhibitor targeting Frizzled-7 (Fzd7), effectively suppressing canonical Wnt/β-catenin signaling. This activity reduces cancer cell viability, making it a valuable tool for in vitro and in vivo research in oncology, particularly for studying Wnt-driven cancers.
Product Specifications
CAS Number
1030769-75-5
Product Name Alternative
FZD7, bcatenin, betacatenin, beta-catenin, Wnt, Wnt/betacatenin, Wnt/b-catenin, Wnt/β-catenin, βcatenin, SRI37892, SRI-37892, SRI 37892
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
98.92% (May vary between batches)
Solubility
DMSO:50 mg/mL (107.4 mM)
Smiles
C (NC1=NC (=CS1) C=2C=C3C (=CC2) NC (=O) CC3) (=O) C4=CC=C (N5C=6C (N=C5) =CC=CC6) C=C4
Molecular Formula
C26H19N5O2S
Molecular Weight
465.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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