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AGI-43192

AGI-43192 is a brain-penetrant, potent inhibitor of methionine adenosyltransferase 2A (MAT2A), blocking S-adenosylmethionine (SAM) production. This tool compound enables research into SAM-dependent processes in the central nervous system and is investigated in oncology for its potential anti-cancer effects in preclinical models.

Product Specifications

CAS Number

2377491-54-6

Product Name Alternative

AGI 43192, AGI43192, AGI-43192, MAT2A

Field of Research

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Purity

99.60% (May vary between batches)

Solubility

DMSO:45 mg/mL (92.81 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:8 mg/mL (16.5 mM)

Smiles

Cn1cc2cc (ccc2n1) -n1cc2cnc (NCC (F) (F) F) nc2c (-c2ccc (Cl) cc2) c1=O

Molecular Formula

C23H16ClF3N6O

Molecular Weight

484.86

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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