AGI-43192
AGI-43192 is a brain-penetrant, potent inhibitor of methionine adenosyltransferase 2A (MAT2A), blocking S-adenosylmethionine (SAM) production. This tool compound enables research into SAM-dependent processes in the central nervous system and is investigated in oncology for its potential anti-cancer effects in preclinical models.
Product Specifications
CAS Number
2377491-54-6
Product Name Alternative
AGI 43192, AGI43192, AGI-43192, MAT2A
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Purity
99.60% (May vary between batches)
Solubility
DMSO:45 mg/mL (92.81 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:8 mg/mL (16.5 mM)
Smiles
Cn1cc2cc (ccc2n1) -n1cc2cnc (NCC (F) (F) F) nc2c (-c2ccc (Cl) cc2) c1=O
Molecular Formula
C23H16ClF3N6O
Molecular Weight
484.86
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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