BLU-945
BLU-945 is a selective, oral EGFR tyrosine kinase inhibitor designed to target resistant mutations like L858R/T790M/C797S. It is a research tool for studying non-small cell lung cancer (NSCLC), demonstrating activity in both in vitro cell line models and in vivo studies.
Product Specifications
CAS Number
2660250-10-0
Product Name Alternative
EGFR, BLU945, BLU-945, BLU 945
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.11% (May vary between batches)
Solubility
DMSO:250 mg/mL (449.07 mM)
Smiles
CO[C@@H]1CCN (C[C@@H]1F) c1nccc (Nc2cc3c (ccc (N4C[C@H] (CS (C) (=O) =O) [C@H]4C) c3cn2) C (C) C) n1
Molecular Formula
C28H37FN6O3S
Molecular Weight
556.7
Storage Conditions
-20°C
Notes
For research use only.
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