NecroX-7
NecroX-7 (LC-280126) is a small molecule with dual functions as a free radical scavenger and an HMGB1 inhibitor. It demonstrates protective effects in models of acetaminophen toxicity and ischemia/reperfusion injury by blocking HMGB1 release and subsequent inflammatory signaling. Research applications include studying inflammatory diseases like graft-versus-host disease (GVHD) in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
1120332-55-9
Product Name Alternative
NADPHoxidase, NADPH-oxidase, NecroX 7, NecroX7, NecroX-7, LC 280126, LC28 0126, LC280126, LC-280126, LC28-0126
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction
Purity
98.08% (May vary between batches)
Smiles
N (C1=C2C (C=C (N2) C3=CC=CC=C3) =CC (CN4CCS (=O) (=O) CC4) =C1) C5CCOCC5
Molecular Formula
C24H29N3O3S
Molecular Weight
439.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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