ElteN378
ElteN378 is a potent, low molecular weight synthetic inhibitor of FKBP12, exhibiting sub-nanomolar affinity (Ki = 0.5 nM) comparable to rapamycin. It serves as a valuable chemical probe for studying FKBP12 function and mTOR signaling pathways in both cellular and animal models of immunology and cancer research.
Product Specifications
CAS Number
1421366-99-5
Product Name Alternative
MTOR (FKBP12), ElteN 378, ElteN378, ElteN-378
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction
Purity
98.09% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.64 mM) ; DMSO:10 mg/mL (26.42 mM)
Smiles
C (C (=O) C1=CC=CC=C1) (=O) N2[C@H] (C (NCCCC3=CC=CC=C3) =O) CCCC2
Molecular Formula
C23H26N2O3
Molecular Weight
378.46
Storage Conditions
-20°C
Notes
For research use only.
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