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ElteN378

ElteN378 is a potent, low molecular weight synthetic inhibitor of FKBP12, exhibiting sub-nanomolar affinity (Ki = 0.5 nM) comparable to rapamycin. It serves as a valuable chemical probe for studying FKBP12 function and mTOR signaling pathways in both cellular and animal models of immunology and cancer research.

Product Specifications

CAS Number

1421366-99-5

Product Name Alternative

MTOR (FKBP12), ElteN 378, ElteN378, ElteN-378

Field of Research

Cell Biology, Immunology & Inflammation, Signal Transduction

Purity

98.09% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.64 mM) ; DMSO:10 mg/mL (26.42 mM)

Smiles

C (C (=O) C1=CC=CC=C1) (=O) N2[C@H] (C (NCCCC3=CC=CC=C3) =O) CCCC2

Molecular Formula

C23H26N2O3

Molecular Weight

378.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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