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GLL 398

GLL 398 is a potent and selective oral estrogen receptor degrader, demonstrating an IC50 of 1.14 nM. It effectively inhibits tumor growth in breast cancer xenograft models, supporting its use in both in vitro mechanistic studies and in vivo preclinical research for hormone receptor-positive cancers.

Product Specifications

CAS Number

2077980-80-2

Field of Research

Metabolism Research

Smiles

CC/C (C1=CC=CC=C1) =C (C2=CC=C (B (O) O) C=C2) /C3=CC=C (C=C3) /C=C/C (O) =O

Molecular Formula

C25H23BO4

Molecular Weight

398.26

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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