Hellebrigenin

Hellebrigenin is a small molecule that inhibits MAPK pathways (ERK, p38, JNK) and XIAP, downregulating Akt and inducing apoptosis via caspase activation and DNA damage. It demonstrates anti-proliferative effects in research models of oral squamous cell carcinoma and liver cancer, both in vitro and in vivo.

Product Specifications

CAS Number

465-90-7

Product Name Alternative

CDK, Akt, PARP, Hellebrigenin

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry, Signal Transduction

Purity

99.98% (May vary between batches)

Smiles

C (=O) [C@@]12[C@@]3 ([C@] ([C@]4 (O) [C@] (C) (CC3) [C@H] (CC4) C=5C=CC (=O) OC5) (CC[C@]1 (O) C[C@@H] (O) CC2) [H]) [H]

Molecular Formula

C24H32O6

Molecular Weight

416.51

Storage Conditions

Keep away from moisture, keep away from direct sunlight, The compound is unstable in solution. Please use soon | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.