Saikogenin D
Saikogenin D is a research compound with dual anti-inflammatory mechanisms: it inhibits PGE2 production without directly suppressing COX and stimulates intracellular calcium release. It also exhibits immunomodulatory properties by differentially attenuating IL-6 production in LPS-stimulated macrophages from different mouse strains, useful for studying calcium signaling and inflammatory pathways in vitro.
Product Specifications
CAS Number
5573-16-0
Product Name Alternative
CalciumChannel, Calcium Channel, ILReceptor, IL Receptor, PGE, Prostaglandin Receptor, ProstaglandinReceptor, Saikogenin D
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery
Purity
99.99% (May vary between batches)
Solubility
DMSO:≥ 80 mg/mL
Smiles
C[C@]12[C@@]3 (C) C (=C4[C@@] (CO) ([C@H] (O) C3) CCC (C) (C) C4) C=C[C@@]1 ([C@]5 (C) [C@@] (CC2) ([C@@] (CO) (C) [C@@H] (O) CC5) [H]) [H]
Molecular Formula
C30H48O4
Molecular Weight
472.7
Storage Conditions
Keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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CXORF66 (Uncharacterized Protein CXorf66, Chromosome X Open Reading Frame 66)
HEY 2 (Helix-loop-helix Transcription Factor, Hairy/enhancer-of-split related with YRPW motif 2, bHLHb32, BHLHB32, Cardiovascular helix-loop-helix factor 1, CHF1, Class B basic helix-loop-helix protein 32, GRIDLOCK, GRL, Hairy and enhancer of split-related protein 2, Hairy-related transcription factor 2, hCHF1, HERP, HERP1, HESR2, HESR-2, HES-related repressor protein 2, hHRT2, HRT2, HRT-2, MGC10720, Protein gridlock homolog (APC)