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Withanolide B

Withanolide B, a natural compound from Withania somnifera, stimulates osteogenesis in hBMSCs by activating ERK1/2 and Wnt/β-catenin signaling, which supports bone regeneration. It also binds the PARP-1 catalytic domain, making it a useful research tool for studying bone healing mechanisms in both cellular and animal models.

Product Specifications

CAS Number

56973-41-2

Field of Research

Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology

Smiles

[H][C@@]1 (CC[C@@]2 ([H]) [C@]3 ([H]) [C@@H]4O[C@@H]4[C@@]4 (O) CC=CC (=O) [C@]4 (C) [C@@]3 ([H]) CC[C@]12C) [C@H] (C) [C@@]1 ([H]) CC (C) =C (C) C (=O) O1

Molecular Formula

C28H38O5

Molecular Weight

454.60

Storage Conditions

-20°C

Notes

For research use only.

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