1beta-Hydroxyalantolactone

1β-Hydroxyalantolactone, isolated from Inula britannica flowers, modulates key inflammatory cytokines. It suppresses cellular expression while promoting secretion of TNF-α, IL-17, and IFN-γ, indicating a complex immunoregulatory role. This compound is used in rheumatoid arthritis research, with studies exploring its mechanisms in both cellular and animal models of inflammation.

Product Specifications

CAS Number

68776-47-6

Product Name Alternative

IL Receptor, ILReceptor, IL-17 production, NF-κB, 1β-Hydroxyalantolactone, 1beta Hydroxyalantolactone, 1b-Hydroxyalantolactone, 1beta-Hydroxyalantolactone, 1betaHydroxyalantolactone, TNF-α

Field of Research

Cell Biology, Immunology & Inflammation, Signal Transduction

Purity

98.09% (May vary between batches)

Smiles

[H][C@@]12C[C@@]3 (C) [C@H] (O) CC[C@H] (C) C3=C[C@]1 ([H]) C (=C) C (=O) O2

Molecular Formula

C15H20O3

Molecular Weight

248.32

Storage Conditions

Store at low temperature, keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.