4,5-Dimethoxycanthin-6-one

4,5-Dimethoxycanthin-6-one is a bioactive alkaloid isolated from Picrasma quassioides. It exhibits antimicrobial activity against Staphylococcus aureus and demonstrates cytotoxicity against tumor cell lines like U937 and HepG2. This compound also acts as a potent, non-competitive inhibitor of CYP1A2 and cAMP phosphodiesterase.

Product Specifications

CAS Number

18110-87-7

Product Name Alternative

4,5-Dimethoxycanthin-6-one, Bacterial, Antifection, cAMP, CAMP PDE, CYP1A2, Cytochrome P450, Methylnigakinone

Field of Research

Infectious Disease & Virology, Metabolism Research

Purity

98.84% (May vary between batches)

Solubility

DMSO:9 mg/mL (32.11 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.57 mM)

Smiles

COc1c (OC) c (=O) n2c3ccccc3c3ccnc1c23

Molecular Formula

C16H12N2O3

Molecular Weight

280.28

Storage Conditions

Store at low temperature, keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.