Durlobactam (sodium)
Product Specifications
UNSPSC Description
Durlobactam sodium salt (ETX2514) is a broad-spectrum β-lactamase inhibitor with IC50s of 4, 14 and 190 nM for Class A KPC-2, Class C AmpC and Class D OXA-24, respectively. For the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii[1].
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Durlobactam_sodium_salt.html
Purity
99.62
Solubility
H2O : ≥ 100 mg/mL
Smiles
NC([C@H]1[N@@]2C(N([C@H](C=C1C)C2)OS(=O)(O[Na])=O)=O)=O
Molecular Weight
299.24
References & Citations
[1]Durand-Réville TF, et al. ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including <i>Acinetobacter baumannii</i>. Nat Microbiol. 2017 Jun 30;2:17104.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-117974/Durlobactam-sodium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-117974/Durlobactam-sodium-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
1467157-21-6
Available Sizes
Curated Selection
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