7-Oxo-beta-sitosterol
7-Oxo-beta-sitosterol (7-Ketositosterol) is a phytosterol with demonstrated anticancer activity. It inhibits HL-60 AML cell proliferation by downregulating S1P, p-ERK1/2, and p-NF-κB p65, leading to ceramide accumulation and apoptosis. This compound is a useful research tool for studying mechanisms in leukemia and breast cancer models.
Product Specifications
CAS Number
2034-74-4
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Smiles
C[C@@]12[C@] ([C@]3 ([C@@] ([C@]4 (C) C (=CC3=O) C[C@@H] (O) CC4) (CC1) [H]) [H]) (CC[C@@]2 ([C@@H] (CC[C@H] (C (C) C) CC) C) [H]) [H]
Molecular Formula
C29H48O2
Molecular Weight
428.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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