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7beta- (3-Ethyl-cis-crotonoyloxy) -1alpha- (2-methylbutyryloxy) -3,14-dehydro-Z-notonipetranone

This small molecule inhibitor of diacylglycerol acyltransferase 1 (DGAT1) exhibits IC50 values of 47.0 μM in rat liver microsomes and 160.7 μM in HepG2 cell microsomes. It is a useful research tool for studying lipid metabolism and triglyceride synthesis in both in vitro and cell-based assays.

Product Specifications

CAS Number

80514-14-3

Smiles

CCC (C) C (=O) O[C@H]1[C@@H]2[C@H] ([C@@H] (C[C@@H] (OC (=O) \C=C (/C) CC) C2=C) C (C) C) \C (=C\C) C1=O

Molecular Formula

C26H38O5

Molecular Weight

430.58

Storage Conditions

-20°C

Notes

For research use only.

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