Excisanin A
Excisanin A is a bioactive small molecule that potently inhibits the AKT/NF-κB signaling pathway, suppressing MMP-2/9 expression and cancer cell invasion. It induces apoptosis in SW620 colon cancer cells and inhibits inflammatory mediators like NO and PGE2 in vitro, highlighting its potential for metastasis and cancer research.
Product Specifications
CAS Number
78536-37-5
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology
Smiles
CC1 (C) CC[C@H] (O) [C@@]2 (C) [C@@H]3C[C@H] (O) [C@@H]4[C@@H] (O) [C@@]3 ([C@H] (O) C[C@H]12) C (=O) C4=C
Molecular Formula
C20H30O5
Molecular Weight
350.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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