Guajadial B
Guajadial B is a catalytic inhibitor of Topoisomerase I (Top1) that mitigates DNA damage induced by Top1 poisons. It exhibits potent cytotoxicity across multiple human cancer cell lines, with an IC50 of 150 nM in A549 lung carcinoma cells, supporting its investigation as an anticancer agent in biochemical and cellular research.
Product Specifications
CAS Number
1414455-03-0
Field of Research
Molecular Biology
Smiles
C\C1=C/CC (C) (C) \C=C\C[C@@]2 (C) Oc3c (C=O) c (O) c (C=O) c (O) c3[C@H] ([C@@H]2CC1) c1ccccc1
Molecular Formula
C30H34O5
Molecular Weight
474.597
Storage Conditions
-20°C
Notes
For research use only.
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