Physalin A
Physalin A, a natural compound from Physalis alkekengi, exhibits anti-inflammatory and anti-fibrotic activity by modulating the Nrf2 pathway via ERK/p38 and inhibiting NF-κB signaling. It also reduces mammosphere formation by downregulating GLI1 and YAP1, making it a useful research tool for studying fibrosis, inflammation, and cancer stem cells in vitro.
Product Specifications
CAS Number
23027-91-0
Product Name Alternative
ERK, p53, NF-κB, JNK, JAK, Autophagy, Apoptosis, Androgen Receptor, Bcl-2, p38 MAPK, Physalin A, STAT, ROS
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.71% (May vary between batches)
Solubility
DMSO:55.34 mg/mL (105.1 mM)
Smiles
C[C@@]12[C@]34[C@] ([C@]5 (C) C[C@]1 (OC (=O) C5=C) [H]) (C (=O) [C@] (O) (O3) [C@]6 ([C@] (CC[C@]4 (O) C (=O) O2) ([C@]7 (C) C (=C[C@H]6O) CC=CC7=O) [H]) [H]) [H]
Molecular Formula
C28H30O10
Molecular Weight
526.53
Storage Conditions
Keep away from moisture, keep away from direct sunlight, store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
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