Physalin H
Physalin H is a Hedgehog signaling inhibitor that blocks GLI1-DNA complex formation and exhibits quinone reductase induction. It demonstrates immunosuppressive effects on T cells in vitro and in vivo, along with cytotoxic activity against various cancer cell lines and leishmanicidal activity against Leishmania major promastigotes.
Product Specifications
CAS Number
70241-09-7
Field of Research
Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Smiles
C[C@]12[C@]34[C@]5 ([C@@]6 (C) [C@@] (CO[C@] (O3) (C5=O) [C@]7 ([C@] (CC[C@@]4 (O) C (=O) O1) ([C@]8 (C) [C@@] (Cl) ([C@H] (O) C7) CC=CC8=O) [H]) [H]) (C (=O) O[C@@H]2C6) [H]) [H]
Molecular Formula
C28H31ClO10
Molecular Weight
562.99
Storage Conditions
-20°C
Notes
For research use only.
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