(±) -1,2-Propanediol

(±) -1, 2-propanediol (1,2- (RS) -Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±) -1, 2-propanediol can affect the neurobehavior of zebrafish[1][2].

Product Specifications

CAS Number

[57-55-6]

Product Name Alternative

1,2- (RS) -Propanediol; 1,2-Propylene glycol; Propylene glycol

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/__plusmn__-1,2-Propanediol.html

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)

Smiles

CC(O)CO

Molecular Formula

C3H8O2

Molecular Weight

76.09

Precautions

H302, H315, H319, H335

References & Citations

[1]De Cock RF, et al. Low but inducible contribution of renal elimination to clearance of propylene glycol in preterm and term neonates. Ther Drug Monit. 2014 Jun;36 (3) :278-87.|[2]Massarsky A, et al. Neurobehavioral effects of 1,2-propanediol in zebrafish (Danio rerio) . Neurotoxicology. 2018 Mar;65:111-124.