Semialactone
Semialactone is a dual inhibitor of human ACAT-1 and ACAT-2 enzymes, exhibiting IC50 values of approximately 79.1 μM and 76.9 μM, respectively. This activity suggests its potential utility as a research tool for investigating cholesterol metabolism, hypercholesterolemia, and atherosclerosis in experimental models.
Product Specifications
CAS Number
366450-46-6
Smiles
C\C1=C\C[C@H] (O) C (=C) [C@H]2CC[C@]3 (COC1=O) [C@@H]2CC[C@H]1[C@@]3 (C) CCC2C (C) (C) [C@@]3 (O) CC[C@]12CO3
Molecular Formula
C30H44O4
Molecular Weight
468.67
Storage Conditions
-20°C
Notes
For research use only.
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