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Semialactone

Semialactone is a dual inhibitor of human ACAT-1 and ACAT-2 enzymes, exhibiting IC50 values of approximately 79.1 μM and 76.9 μM, respectively. This activity suggests its potential utility as a research tool for investigating cholesterol metabolism, hypercholesterolemia, and atherosclerosis in experimental models.

Product Specifications

CAS Number

366450-46-6

Smiles

C\C1=C\C[C@H] (O) C (=C) [C@H]2CC[C@]3 (COC1=O) [C@@H]2CC[C@H]1[C@@]3 (C) CCC2C (C) (C) [C@@]3 (O) CC[C@]12CO3

Molecular Formula

C30H44O4

Molecular Weight

468.67

Storage Conditions

-20°C

Notes

For research use only.

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