Serpentine
Serpentine, an alkaloid from Rosa centifolia roots, acts as an insulin sensitizer by activating AMPK phosphorylation to stimulate glucose uptake in cells like C2C12. It modulates pathways involving GSK-3β and hepatic gluconeogenesis, demonstrating effects in HFD/STZ-induced diabetic mouse models relevant to diabetes research.
Product Specifications
CAS Number
18786-24-8
Field of Research
Signal Transduction
Smiles
C (OC) (=O) C=1[C@]2 (CC=3C4=C (C=5C (N4) =CC=CC5) C=C[N+]3C[C@@]2 ([C@H] (C) OC1) [H]) [H]
Molecular Formula
C21H21N2O3
Molecular Weight
349.4
Storage Conditions
-20°C
Notes
For research use only.
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