CD24/Siglec-10 blocking peptide, CSBP
CD24/Siglec-10 blocking peptide, CSBP can not only block the interaction of CD24/Siglec-10 but also PD-1/PD-L1. CD24/Siglec-10 blocking peptide, CSBP can induce the phagocytosis of tumor cell[1].
Product Specifications
UNSPSC
12352209
Target
PD-1/PD-L1
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cd24-siglec-10-blocking-peptide-csbp.html
Purity
98.91
Solubility
DMSO : 10 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)
Smiles
O=C(O)CC[C@H](C(O)=O)NC([C@@H](CO)NC([C@@H](CC1=CC=C(O)C=C1)NC([C@@H](CC(C)C)NC([C@@H](CC2=CC=CC=C2)NC([C@@H](C(C)C)NC([C@@H](CC(O)=O)NC([C@@H](CC(C)C)N)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C47H68N8O15
Molecular Weight
985.09
References & Citations
[1]Wenhui Shen, et al. Discovery of a novel dual-targeting D-peptide to block CD24/Siglec-10 and PD-1/PD-L1 interaction and synergize with radiotherapy for cancer immunotherapy. J Immunother Cancer. 2023 Jun;11 (6) :e007068.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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