5 (S) -HETE lactone
5 (S) -HETE lactone is a cyclic ester formed via intramolecular acid-catalyzed esterification of 5 (S) -HETE. It acts as an inhibitor of 5-lipoxygenase (IC50 = 27 μM in rat basophilic leukemia cells), making it a useful biochemical tool for studying eicosanoid and leukotriene pathways in vitro.
Product Specifications
CAS Number
127708-42-3
Field of Research
Metabolism Research
Smiles
C (=C/C=C\C/C=C\C/C=C\CCCCC) \[C@H]1OC (=O) CCC1
Molecular Formula
C20H30O2
Molecular Weight
302.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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