3-Aminopropylphosphonic Acid
3-Aminopropylphosphonic acid (3-APPA) is a phosphonate structural analog of γ-aminobutyric acid (GABA) . It functions as a partial agonist at GABAB receptors, exhibiting an IC50 of 1.5 μM in binding assays. This compound is utilized in neuroscience research to study GABAB receptor pharmacology and signaling in both cellular and animal models.
Product Specifications
CAS Number
13138-33-5
Product Name Alternative
3 Aminopropylphosphonic Acid, 3Aminopropylphosphonic Acid, 3-Aminopropylphosphonic Acid, GABA Receptor, GABAReceptor, GABAB
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.90% (May vary between batches)
Solubility
Ethanol:PBS (pH 7.2) (1:3) :0.25 mg/mL (1.8 mM) ; H2O:105 mg/mL (754.91 mM) ; DMF:5 mg/mL (35.95 mM) ; Ethanol:30 mg/mL (215.69 mM) ; DMSO:< 1 mg/mL (insoluble or slightly soluble)
Smiles
NCCCP (O) (O) =O
Molecular Formula
C3H10NO3P
Molecular Weight
139.09
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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