TBK1/IKKε-IN-4
TBK1/IKKε-IN-4 is a highly selective 6-aminopyrazolopyrimidine inhibitor of TBK1 (IC50=13 nM) and IKKε (IC50=59 nM) . It shows minimal off-target activity against related kinases and is a valuable tool for studying innate immunity, inflammation, and oncology in cellular and in vivo models.
Product Specifications
CAS Number
1381930-17-1
Field of Research
Signal Transduction
Smiles
COc1ccc (cc1) -n1ncc2cnc (Nc3cc (OC) c (OC) c (OCCCN4CCN (C) CC4) c3) nc12
Molecular Formula
C28H35N7O4
Molecular Weight
533.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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