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TBK1/IKKε-IN-4

TBK1/IKKε-IN-4 is a highly selective 6-aminopyrazolopyrimidine inhibitor of TBK1 (IC50=13 nM) and IKKε (IC50=59 nM) . It shows minimal off-target activity against related kinases and is a valuable tool for studying innate immunity, inflammation, and oncology in cellular and in vivo models.

Product Specifications

CAS Number

1381930-17-1

Field of Research

Signal Transduction

Smiles

COc1ccc (cc1) -n1ncc2cnc (Nc3cc (OC) c (OC) c (OCCCN4CCN (C) CC4) c3) nc12

Molecular Formula

C28H35N7O4

Molecular Weight

533.62

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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