PF-04577806
PF-04577806 is a potent, ATP-competitive inhibitor selective for multiple PKC isoforms, including PKCα, βI, βII, γ, and θ. It demonstrates efficacy in preclinical models, such as reversing retinal vascular leakage in diabetic rats, supporting its research use in studying PKC-related pathways in diabetes and vascular biology.
Product Specifications
CAS Number
1072100-81-2
Field of Research
Epigenetics & Chromatin, Metabolism Research, Signal Transduction
Smiles
C[C@@H]1CN ([C@@H] (C) CN1CC1CCOCC1) C (=O) N1Cc2c (NC (=O) c3ccccn3) n[nH]c2C1 (C) C
Molecular Formula
C26H37N7O3
Molecular Weight
495.628
Storage Conditions
-20°C
Notes
For research use only.
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