RMC-4529
RMC-4529 is a potent and selective mTOR kinase inhibitor, demonstrating an IC50 of 1.0 nM against phospho-4E-BP1 (T37/46) in cellular assays. This small molecule is a valuable research tool for studying mTOR signaling in cancer and metabolic diseases, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2250059-27-7
Field of Research
Signal Transduction
Smiles
[H][C@@]12CC[C@@H] (C) [C@@] (O) (O1) C (=O) C (=O) N1CCCC[C@@]1 ([H]) C (=O) O[C@@] ([H]) (C[C@@H] (OC) [C@H] (C) \C=C (C) /[C@@H] (O) [C@@H] (OC) C (=NOCc1cn (CCOCCOCCOCCOCCOCCOCCOCCOCCC (=O) NCCCCn3nc (-c4ccc5oc (N) nc5c4) c4c (N) ncnc34) nn1) [C@H] (C) C[C@H] (C) \C=C/C=C\C=C (C) /[C@H] (C2) OC) [C@H] (C) C[C@@H]1CC[C@@H] (O) [C@@H] (C1) OC |w:40.42, c:113,115, t:33,117|
Molecular Formula
C90H139N13O23
Molecular Weight
1771.17
Storage Conditions
-20°C
Notes
For research use only.
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