Bcl-2-IN-2
Bcl-2-IN-2 is a potent and highly selective Bcl-2 inhibitor, exhibiting an IC50 of 0.034 nM for Bcl-2 and >1000-fold selectivity over Bcl-xL (IC50=43 nM) . This small molecule is a valuable research tool for studying apoptosis mechanisms and has been utilized in both in vitro and in vivo cancer research models.
Product Specifications
CAS Number
2383085-86-5
Field of Research
Cell Biology
Smiles
CCc1ccccc1[C@@H]1CCCN1C1CC2 (C1) CCN (CC2) c1ccc (C (=O) NS (=O) (=O) c2ccc (NC[C@H]3CC[C@] (C) (O) CC3) c (c2) N (=O) =O) c (Oc2cnc3[nH]ccc3c2) c1 |wU:8.8,41.46, wD:38.41,41.45, (10.07,9.11, ;9.75,10.61, ;10.9,11.64, ;12.36,11.17, ;13.5,12.2, ;13.18,13.7, ;11.72,14.18, ;10.58,13.15, ;9.11,13.63, ;8.64,15.09, ;7.1,15.09, ;6.62,13.63, ;7.87,12.72, ;7.87,11.18, ;8.95,10.09, ;7.87,9, ;6.78,10.09, ;9.2,8.23, ;9.2,6.69, ;7.87,5.92, ;6.53,6.69, ;6.53,8.23, ;7.87,4.38, ;9.2,3.61, ;9.2,2.07, ;7.87,1.3, ;7.87, -.24, ;6.53, -1.01, ;9.2, -1.01, ;10.53, -.24, ;9.76,1.1, ;11.3, -1.57, ;11.87, .53, ;13.2, -.24, ;14.53, .53, ;14.53,2.07, ;15.87,2.84, ;15.87,4.38, ;17.2,5.15, ;18.53,4.38, ;19.87,5.15, ;19.87,6.69, ;20.4,8.14, ;21.38,6.43, ;18.53,7.46, ;17.2,6.69, ;13.2,2.84, ;11.87,2.07, ;13.2,4.38, ;14.53,5.15, ;11.87,5.15, ;6.53,2.07, ;5.2,1.3, ;3.86,2.07, ;3.86,3.61, ;2.53,4.38, ;1.2,3.61, ; -.27,4.09, ; -1.17,2.84, ; -.27,1.6, ;1.2,2.07, ;2.53,1.3, ;6.53,3.61, ) |
Molecular Formula
C48H57N7O7S
Molecular Weight
876.09
Storage Conditions
-20°C
Notes
For research use only.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
