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GSK872

GSK-872 is a potent and selective RIP3 kinase inhibitor, exhibiting high-affinity binding and inhibitory activity in the low nanomolar range. This compound is a valuable research tool for investigating necroptosis in both cellular and animal models, aiding the study of inflammatory and neurodegenerative diseases.

Product Specifications

CAS Number

1346546-69-7

Product Name Alternative

GSK2399872A; GSK’872

Field of Research

Cell Biology, Immunology & Inflammation, Neuroscience

Purity

>98%

Bioactivity

Necroptosis inhibitor / RIP3 inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to at least 25 mg/ml)

Smiles

CC (C) S (=O) (=O) c1ccc2nccc (Nc3ccc4scnc4c3) c2c1

Molecular Formula

C19H17N3O2S2

Molecular Weight

383.5

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

N- (6-Propan-2-ylsulfonylquinolin-4-yl) -1,3-benzothiazol-5-amine

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